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Aging augments obesity-induced thymic involution and peripheral T cell exhaustion altering the “obesity paradox”
INTRODUCTION: The incidence of obesity, a condition characterized by systemic chronic inflammation, has reached pandemic proportions and is a poor prognostic factor in many pathologic states. However, its role on immune parameters has been diverse and at times contradictory. We have previously demon...
Autores principales: | Vick, Logan V., Collins, Craig P., Khuat, Lam T., Wang, Ziming, Dunai, Cordelia, Aguilar, Ethan G., Stoffel, Kevin, Yendamuri, Sai, Smith, Randall, Mukherjee, Sarbajit, Barbi, Joseph, Canter, Robert J., Monjazeb, Arta M., Murphy, William J. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9910174/ https://www.ncbi.nlm.nih.gov/pubmed/36776393 http://dx.doi.org/10.3389/fimmu.2022.1012016 |
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