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Lipid kinase PIK3C3 maintains healthy brown and white adipose tissues to prevent metabolic diseases

Adequate mass and function of adipose tissues (ATs) play essential roles in preventing metabolic perturbations. The pathological reduction of ATs in lipodystrophy leads to an array of metabolic diseases. Understanding the underlying mechanisms may benefit the development of effective therapies. Seve...

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Detalles Bibliográficos
Autores principales: Song, Wenqiang, Postoak, J. Luke, Yang, Guan, Guo, Xingyi, Pua, Heather H., Bader, Jackie, Rathmell, Jeffrey C., Kobayashi, Hanako, Haase, Volker H., Leaptrot, Katrina L., Schrimpe-Rutledge, Alexandra C., Sherrod, Stacy D., McLean, John A., Zhang, Jianhua, Wu, Lan, Van Kaer, Luc
Formato: Online Artículo Texto
Lenguaje:English
Publicado: National Academy of Sciences 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9910429/
https://www.ncbi.nlm.nih.gov/pubmed/36574710
http://dx.doi.org/10.1073/pnas.2214874120