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Kidney-resident innate-like memory γδ T cells control chronic Staphylococcus aureus infection of mice

γδ T cells are involved in the control of Staphylococcus aureus infection, but their importance in protection compared to other T cells is unclear. We used a mouse model of systemic S. aureus infection associated with high bacterial load and persistence in the kidney. Infection caused fulminant accu...

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Detalles Bibliográficos
Autores principales: Bertram, Tabea, Reimers, Daniel, Lory, Niels C., Schmidt, Constantin, Schmid, Joanna, C. Heinig, Lisa, Bradtke, Peter, Rattay, Guido, Zielinski, Stephanie, Hellmig, Malte, Bartsch, Patricia, Rohde, Holger, Nuñez, Sarah, Rosemblatt, Mariana V., Bono, Maria Rosa, Gagliani, Nicola, Sandrock, Inga, Panzer, Ulf, Krebs, Christian F., Meyer-Schwesinger, Catherine, Prinz, Immo, Mittrücker, Hans-Willi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: National Academy of Sciences 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9910431/
https://www.ncbi.nlm.nih.gov/pubmed/36574651
http://dx.doi.org/10.1073/pnas.2210490120