The direct binding of Plasmodium vivax AMA1 to erythrocytes defines a RON2-independent invasion pathway

We used a transgenic parasite in which Plasmodium falciparum parasites were genetically modified to express Plasmodium vivax apical membrane antigen 1 (PvAMA1) protein in place of PfAMA1 to study PvAMA1-mediated invasion. In P. falciparum, AMA1 interaction with rhoptry neck protein 2 (RON2) is known...

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Detalles Bibliográficos
Autores principales: Lee, Seong-Kyun, Low, Leanne M., Andersen, John F., Yeoh, Lee M., Valenzuela Leon, Paola Carolina, Drew, Damien R., Doehl, Johannes S. P., Calvo, Eric, Miller, Louis H., Beeson, James G., Gunalan, Karthigayan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: National Academy of Sciences 2022
Materias:
Biological Sciences
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9910450/
https://www.ncbi.nlm.nih.gov/pubmed/36577076
http://dx.doi.org/10.1073/pnas.2215003120

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9910450/
https://www.ncbi.nlm.nih.gov/pubmed/36577076
http://dx.doi.org/10.1073/pnas.2215003120

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