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The direct binding of Plasmodium vivax AMA1 to erythrocytes defines a RON2-independent invasion pathway
We used a transgenic parasite in which Plasmodium falciparum parasites were genetically modified to express Plasmodium vivax apical membrane antigen 1 (PvAMA1) protein in place of PfAMA1 to study PvAMA1-mediated invasion. In P. falciparum, AMA1 interaction with rhoptry neck protein 2 (RON2) is known...
Autores principales: | Lee, Seong-Kyun, Low, Leanne M., Andersen, John F., Yeoh, Lee M., Valenzuela Leon, Paola Carolina, Drew, Damien R., Doehl, Johannes S. P., Calvo, Eric, Miller, Louis H., Beeson, James G., Gunalan, Karthigayan |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
National Academy of Sciences
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9910450/ https://www.ncbi.nlm.nih.gov/pubmed/36577076 http://dx.doi.org/10.1073/pnas.2215003120 |
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