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SUMO enhances unfolding of SUMO–polyubiquitin-modified substrates by the Ufd1/Npl4/Cdc48 complex

The Ufd1/Npl4/Cdc48 complex is a universal protein segregase that plays key roles in eukaryotic cellular processes. Its functions orchestrating the clearance or removal of polyubiquitylated targets are established; however, prior studies suggest that the complex also targets substrates modified by t...

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Detalles Bibliográficos
Autores principales: Lee, Hyein G., Lemmon, Abigail A., Lima, Christopher D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: National Academy of Sciences 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9910466/
https://www.ncbi.nlm.nih.gov/pubmed/36574706
http://dx.doi.org/10.1073/pnas.2213703120