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High-speed imaging reveals the bimodal nature of dense core vesicle exocytosis

During exocytosis, the fusion of secretory vesicle with plasma membrane forms a pore that regulates release of neurotransmitter and peptide. Heterogeneity of fusion pore behavior has been attributed to stochastic variation in a common exocytic mechanism, implying a lack of biological control. Using...

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Detalles Bibliográficos
Autores principales: Zhang, Pengcheng, Rumschitzki, David, Edwards, Robert H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: National Academy of Sciences 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9910497/
https://www.ncbi.nlm.nih.gov/pubmed/36574702
http://dx.doi.org/10.1073/pnas.2214897120