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SARS-CoV-2 RNA-dependent RNA polymerase as a target for high-throughput drug screening

The ongoing COVID-19 pandemic caused by the SARS-CoV-2 has necessitated rapid development of drug screening tools. RNA-dependent RNA polymerase (RdRp) is a promising target due to its essential functions in replication and transcription of viral genome. To date, through minimal RNA synthesizing mach...

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Detalles Bibliográficos
Autores principales: Wu, Jiahui, Chen, Zhiqiang, Han, Xue, Chen, Qiaoqiao, Wang, Yintao, Feng, Tingting
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Future Medicine Ltd 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9910510/
https://www.ncbi.nlm.nih.gov/pubmed/36794167
http://dx.doi.org/10.2217/fvl-2021-0335