SPOP loss of function protects against tauopathy

The pathological accumulation of the microtubule binding protein tau drives age-related neurodegeneration in a variety of disorders, collectively called tauopathies. In the most common tauopathy, Alzheimer’s disease (AD), the accumulation of pathological tau strongly correlates with cognitive declin...

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Detalles Bibliográficos
Autores principales: Eck, Randall J., Kow, Rebecca L., Black, Aristide H., Liachko, Nicole F., Kraemer, Brian C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: National Academy of Sciences 2022
Materias:
Biological Sciences
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9910588/
https://www.ncbi.nlm.nih.gov/pubmed/36574656
http://dx.doi.org/10.1073/pnas.2207250120

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9910588/
https://www.ncbi.nlm.nih.gov/pubmed/36574656
http://dx.doi.org/10.1073/pnas.2207250120

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