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Discovery of antibodies and cognate surface targets for ovarian cancer by surface profiling

Although antibodies targeting specific tumor-expressed antigens are the standard of care for some cancers, the identification of cancer-specific targets amenable to antibody binding has remained a bottleneck in development of new therapeutics. To overcome this challenge, we developed a high-throughp...

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Detalles Bibliográficos
Autores principales: Schröfelbauer, Bärbel, Kimes, Patrick K., Hauke, Paige, Reid, Charlotte E., Shao, Kevin, Hill, Sarah J., Irizarry, Rafael, Hahn, William C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: National Academy of Sciences 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9910589/
https://www.ncbi.nlm.nih.gov/pubmed/36574667
http://dx.doi.org/10.1073/pnas.2206751120