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Extracellular matrix physical properties govern the diffusion of nanoparticles in tumor microenvironment

Nanoparticles (NPs) are confronted with limited and disappointing delivery efficiency in tumors clinically. The tumor extracellular matrix (ECM), whose physical traits have recently been recognized as new hallmarks of cancer, forms a main steric obstacle for NP diffusion, yet the role of tumor ECM p...

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Detalles Bibliográficos
Autores principales: He, Xiaocong, Yang, Yuanyuan, Han, Yulong, Cao, Chunyu, Zhang, Zhongbin, Li, Lingxiao, Xiao, Cailan, Guo, Hui, Wang, Lin, Han, Lichun, Qu, Zhiguo, Liu, Na, Han, Shuang, Xu, Feng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: National Academy of Sciences 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9910605/
https://www.ncbi.nlm.nih.gov/pubmed/36574668
http://dx.doi.org/10.1073/pnas.2209260120