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Obesity triggers tumoral senescence and renders poorly immunogenic malignancies amenable to senolysis
Obesity is a major risk factor for cancer. Conventional thought suggests that elevated adiposity predisposes to heightened inflammatory stress and potentiates tumor growth, yet underlying mechanisms remain ill-defined. Here, we show that tumors from patients with a body mass index >35 carry a hig...
| Autores principales: | , , , , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
National Academy of Sciences
2022
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9910606/ https://www.ncbi.nlm.nih.gov/pubmed/36574648 http://dx.doi.org/10.1073/pnas.2209973120 |