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Identification of a unique subset of tissue-resident memory CD4(+) T cells in Crohn’s disease

T cells differentiate into highly diverse subsets and display plasticity depending on the environment. Although lymphocytes are key mediators of inflammation, functional specialization of T cells in inflammatory bowel disease (IBD) has not been effectively described. Here, we performed deep profilin...

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Detalles Bibliográficos
Autores principales: Yokoi, Takehito, Murakami, Mari, Kihara, Takako, Seno, Shigeto, Arase, Mitsuru, Wing, James Badger, Søndergaard, Jonas Nørskov, Kuwahara, Ryuichi, Minagawa, Tomohiro, Oguro-Igashira, Eri, Motooka, Daisuke, Okuzaki, Daisuke, Mori, Ryota, Ikeda, Atsuyo, Sekido, Yuki, Amano, Takahiro, Iijima, Hideki, Ozono, Keiichi, Mizushima, Tsunekazu, Hirota, Seiichi, Ikeuchi, Hiroki, Takeda, Kiyoshi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: National Academy of Sciences 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9910620/
https://www.ncbi.nlm.nih.gov/pubmed/36574662
http://dx.doi.org/10.1073/pnas.2204269120