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Vitamin D (1α,25(OH)(2)D(3)) supplementation minimized multinucleated giant cells formation and inflammatory response during Burkholderia pseudomallei infection in human lung epithelial cells

Melioidosis is an infectious disease with high mortality rates in human, caused by the bacterium Burkholderia pseudomallei. As an intracellular pathogen, B. pseudomallei can escape from the phagosome and induce multinucleated giant cells (MNGCs) formation resulting in antibiotic resistance and immun...

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Detalles Bibliográficos
Autores principales: Mattrasongkram, Pohnratchada, Wongkaewkhiaw, Saharut, Taweechaisupapong, Suwimol, Chareonsudjai, Sorujsiri, Techawiwattanaboon, Teerasit, Ngamsiri, Thararin, Kanthawong, Sakawrat
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9910702/
https://www.ncbi.nlm.nih.gov/pubmed/36758060
http://dx.doi.org/10.1371/journal.pone.0280944