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Vitamin D (1α,25(OH)(2)D(3)) supplementation minimized multinucleated giant cells formation and inflammatory response during Burkholderia pseudomallei infection in human lung epithelial cells
Melioidosis is an infectious disease with high mortality rates in human, caused by the bacterium Burkholderia pseudomallei. As an intracellular pathogen, B. pseudomallei can escape from the phagosome and induce multinucleated giant cells (MNGCs) formation resulting in antibiotic resistance and immun...
Autores principales: | Mattrasongkram, Pohnratchada, Wongkaewkhiaw, Saharut, Taweechaisupapong, Suwimol, Chareonsudjai, Sorujsiri, Techawiwattanaboon, Teerasit, Ngamsiri, Thararin, Kanthawong, Sakawrat |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9910702/ https://www.ncbi.nlm.nih.gov/pubmed/36758060 http://dx.doi.org/10.1371/journal.pone.0280944 |
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