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Two oxytocin analogs, N-(p-fluorobenzyl) glycine and N-(3-hydroxypropyl) glycine, induce uterine contractions ex vivo in ways that differ from that of oxytocin

Contraction of the uterus is critical for parturient processes. Insufficient uterine tone, resulting in atony, can potentiate postpartum hemorrhage; thus, it is a major risk factor and is the main cause of maternity-related deaths worldwide. Oxytocin (OT) is recommended for use in combination with o...

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Detalles Bibliográficos
Autores principales: Cherepanov, Stanislav M., Yuhi, Teruko, Iizuka, Takashi, Hosono, Takashi, Ono, Masanori, Fujiwara, Hiroshi, Yokoyama, Shigeru, Shuto, Satoshi, Higashida, Haruhiro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9910740/
https://www.ncbi.nlm.nih.gov/pubmed/36758056
http://dx.doi.org/10.1371/journal.pone.0281363