Functional analysis of 110 phosphorylation sites on the circadian clock protein FRQ identifies clusters determining period length and temperature compensation

In the negative feedback loop driving the Neurospora circadian oscillator, the negative element, FREQUENCY (FRQ), inhibits its own expression by promoting phosphorylation of its heterodimeric transcriptional activators, White Collar-1 (WC-1) and WC-2. FRQ itself also undergoes extensive time-of-day-...

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Detalles Bibliográficos
Autores principales: Wang, Bin, Stevenson, Elizabeth-Lauren, Dunlap, Jay C
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2022
Materias:
Investigation
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9911066/
https://www.ncbi.nlm.nih.gov/pubmed/36537198
http://dx.doi.org/10.1093/g3journal/jkac334

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9911066/
https://www.ncbi.nlm.nih.gov/pubmed/36537198
http://dx.doi.org/10.1093/g3journal/jkac334

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