Development and applications of a CRISPR activation system for facile genetic overexpression in Candida albicans

For the fungal pathogen Candida albicans, genetic overexpression readily occurs via a diversity of genomic alterations, such as aneuploidy and gain-of-function mutations, with important consequences for host adaptation, virulence, and evolution of antifungal drug resistance. Given the important role...

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Detalles Bibliográficos
Autores principales: Gervais, Nicholas C, La Bella, Alyssa A, Wensing, Lauren F, Sharma, Jehoshua, Acquaviva, Victoria, Best, Madison, Cadena López, Ricardo Omar, Fogal, Meea, Uthayakumar, Deeva, Chavez, Alejandro, Santiago-Tirado, Felipe, Flores-Mireles, Ana L, Shapiro, Rebecca S
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2022
Materias:
Fungal Genetics and Genomics
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9911074/
https://www.ncbi.nlm.nih.gov/pubmed/36450451
http://dx.doi.org/10.1093/g3journal/jkac301

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9911074/
https://www.ncbi.nlm.nih.gov/pubmed/36450451
http://dx.doi.org/10.1093/g3journal/jkac301

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