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α-hederin overcomes hypoxia-mediated drug resistance in colorectal cancer by inhibiting the AKT/Bcl2 pathway

Currently, chemoresistance is a major challenge that directly affects the prognosis of patients with colorectal cancer (CRC). In addition, hypoxia is associated with poor prognosis and therapeutic resistance in patients with cancer. Accumulating evidence has shown that α-hederin has significant anti...

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Detalles Bibliográficos
Autores principales: Chen, Jinbao, Xu, Jian, Yang, Jiahua, Zhan, Yueping, Li, Sen, Jia, Linlin, Wu, Wentao, Si, Xianke, Zhang, Die, Yu, Kun, Yin, Peihao, Cao, Yijun, Deng, Wanli, Xu, Ke, Li, Wei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9911077/
https://www.ncbi.nlm.nih.gov/pubmed/36704835
http://dx.doi.org/10.3892/ijo.2023.5481