De novo genes with an lncRNA origin encode unique human brain developmental functionality

Human de novo genes can originate from neutral long non-coding RNA (lncRNA) loci and are evolutionarily significant in general, yet how and why this all-or-nothing transition to functionality happens remains unclear. Here, in 74 human/hominoid-specific de novo genes, we identified distinctive U1 ele...

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Detalles Bibliográficos
Autores principales: An, Ni A., Zhang, Jie, Mo, Fan, Luan, Xuke, Tian, Lu, Shen, Qing Sunny, Li, Xiangshang, Li, Chunqiong, Zhou, Fanqi, Zhang, Boya, Ji, Mingjun, Qi, Jianhuan, Zhou, Wei-Zhen, Ding, Wanqiu, Chen, Jia-Yu, Yu, Jia, Zhang, Li, Shu, Shaokun, Hu, Baoyang, Li, Chuan-Yun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9911349/
https://www.ncbi.nlm.nih.gov/pubmed/36593289
http://dx.doi.org/10.1038/s41559-022-01925-6

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9911349/
https://www.ncbi.nlm.nih.gov/pubmed/36593289
http://dx.doi.org/10.1038/s41559-022-01925-6

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