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ELI trifocal microscope: a precise system to prepare target cryo-lamellae for in situ cryo-ET study
Cryo-electron tomography (cryo-ET) has become a powerful approach to study the high-resolution structure of cellular macromolecular machines in situ. However, the current correlative cryo-fluorescence and electron microscopy lacks sufficient accuracy and efficiency to precisely prepare cryo-lamellae...
Autores principales: | , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group US
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9911351/ https://www.ncbi.nlm.nih.gov/pubmed/36646897 http://dx.doi.org/10.1038/s41592-022-01748-0 |