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A CpG island-encoded mechanism protects genes from premature transcription termination

Transcription must be tightly controlled to regulate gene expression and development. However, our understanding of the molecular mechanisms that influence transcription and how these are coordinated in cells to ensure normal gene expression remains rudimentary. Here, by dissecting the function of t...

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Detalles Bibliográficos
Autores principales: Hughes, Amy L., Szczurek, Aleksander T., Kelley, Jessica R., Lastuvkova, Anna, Turberfield, Anne H., Dimitrova, Emilia, Blackledge, Neil P., Klose, Robert J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9911701/
https://www.ncbi.nlm.nih.gov/pubmed/36759609
http://dx.doi.org/10.1038/s41467-023-36236-2