The AP-1 transcription factor Fosl-2 drives cardiac fibrosis and arrhythmias under immunofibrotic conditions

Fibrotic changes in the myocardium and cardiac arrhythmias represent fatal complications in systemic sclerosis (SSc), however the underlying mechanisms remain elusive. Mice overexpressing transcription factor Fosl-2 (Fosl-2(tg)) represent animal model of SSc. Fosl-2(tg) mice showed interstitial card...

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Detalles Bibliográficos
Autores principales: Stellato, Mara, Dewenter, Matthias, Rudnik, Michal, Hukara, Amela, Özsoy, Çagla, Renoux, Florian, Pachera, Elena, Gantenbein, Felix, Seebeck, Petra, Uhtjaerv, Siim, Osto, Elena, Razansky, Daniel, Klingel, Karin, Henes, Joerg, Distler, Oliver, Błyszczuk, Przemysław, Kania, Gabriela
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9911788/
https://www.ncbi.nlm.nih.gov/pubmed/36759717
http://dx.doi.org/10.1038/s42003-023-04534-6

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9911788/
https://www.ncbi.nlm.nih.gov/pubmed/36759717
http://dx.doi.org/10.1038/s42003-023-04534-6

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