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A method for an unbiased estimate of cross-ancestry genetic correlation using individual-level data

Cross-ancestry genetic correlation is an important parameter to understand the genetic relationship between two ancestry groups. However, existing methods cannot properly account for ancestry-specific genetic architecture, which is diverse across ancestries, producing biased estimates of cross-ances...

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Detalles Bibliográficos
Autores principales: Momin, Md. Moksedul, Shin, Jisu, Lee, Soohyun, Truong, Buu, Benyamin, Beben, Lee, S. Hong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9911789/
https://www.ncbi.nlm.nih.gov/pubmed/36759513
http://dx.doi.org/10.1038/s41467-023-36281-x