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Novel TLR7/8 agonists promote activation of HIV-1 latent reservoirs and human T and NK cells

Antiretroviral therapy can successfully suppress HIV-1 replication to undetectable levels but fails to eliminate latent and persistent HIV-1 reservoirs. Recent studies have focused on the immunomodulatory agents such as Toll-like receptor 7 and 8 (TLR7 and TLR8) capable of activating, thereby render...

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Detalles Bibliográficos
Autores principales: Li, Yangyang, Wang, Zhisong, Hou, Ying, Liu, Xiaoyu, Hong, Junxian, Shi, Xuanling, Huang, Xiaojie, Zhang, Tong, Liao, Xuebin, Zhang, Linqi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9911797/
https://www.ncbi.nlm.nih.gov/pubmed/36778871
http://dx.doi.org/10.3389/fmicb.2023.1033448