Dopamine-induced arrestin recruitment and desensitization of the dopamine D4 receptor is regulated by G protein-coupled receptor kinase-2

The dopamine D(4) receptor (D(4)R) is expressed in the retina, prefrontal cortex, and autonomic nervous system and has been implicated in attention deficit hyperactivity disorder (ADHD), substance use disorders, and erectile dysfunction. D(4)R has also been investigated as a target for antipsychotic...

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Detalles Bibliográficos
Autores principales: Burström, Viktor, Ågren, Richard, Betari, Nibal, Valle-León, Marta, Garro-Martínez, Emilio, Ciruela, Francisco, Sahlholm, Kristoffer
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Pharmacology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9911804/
https://www.ncbi.nlm.nih.gov/pubmed/36778010
http://dx.doi.org/10.3389/fphar.2023.1087171

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9911804/
https://www.ncbi.nlm.nih.gov/pubmed/36778010
http://dx.doi.org/10.3389/fphar.2023.1087171

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