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Poly (lactic-co-glycolic acid)-encapsulated iodine-131 nanoparticles fabricated with rhTSH induce apoptosis and immobilization of thyroid cancer cells

BACKGROUND: Aggressive thyroid carcinoma (ATC) usually loses radioiodine avidity to iodine-131 ((131)I) due to the downregulation of sodium/iodide symporter (NIS). The expression of thyroid stimulating hormone receptor (TSHR) is more persistent than NIS and the administration of recombinant human th...

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Detalles Bibliográficos
Autores principales: Fan, Yongzeng, Xiong, Yalan, Wang, Xinhong, Chen, Jiahao, Fang, Danzhou, Huang, Jiahui, Yuan, Gengbiao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9911809/
https://www.ncbi.nlm.nih.gov/pubmed/36776316
http://dx.doi.org/10.3389/fonc.2023.1030105