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Cyclooxygenase-2-Prostaglandin E2 pathway: A key player in tumor-associated immune cells

Cyclooxygenases-2 (COX-2) and Prostaglandin E2 (PGE2), which are important in chronic inflammatory diseases, can increase tumor incidence and promote tumor growth and metastasis. PGE2 binds to various prostaglandin E receptors to activate specific downstream signaling pathways such as PKA pathway, β...

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Detalles Bibliográficos
Autores principales: Jin, Kaipeng, Qian, Chao, Lin, Jinti, Liu, Bing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9911818/
https://www.ncbi.nlm.nih.gov/pubmed/36776289
http://dx.doi.org/10.3389/fonc.2023.1099811