Low-density lipoprotein balances T cell metabolism and enhances response to anti-PD-1 blockade in a HCT116 spheroid model

INTRODUCTION: The discovery of immune checkpoints and the development of their specific inhibitors was acclaimed as a major breakthrough in cancer therapy. However, only a limited patient cohort shows sufficient response to therapy. Hence, there is a need for identifying new checkpoints and predicti...

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Detalles Bibliográficos
Autores principales: Babl, Nathalie, Hofbauer, Joshua, Matos, Carina, Voll, Florian, Menevse, Ayse Nur, Rechenmacher, Michael, Mair, Ruth, Beckhove, Philipp, Herr, Wolfgang, Siska, Peter J., Renner, Kathrin, Kreutz, Marina, Schnell, Annette
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Oncology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9911890/
https://www.ncbi.nlm.nih.gov/pubmed/36776340
http://dx.doi.org/10.3389/fonc.2023.1107484

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9911890/
https://www.ncbi.nlm.nih.gov/pubmed/36776340
http://dx.doi.org/10.3389/fonc.2023.1107484

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