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Clinical trials of self-replicating RNA-based cancer vaccines

Therapeutic cancer vaccines, designed to activate immune effectors against tumor antigens, utilize a number of different platforms for antigen delivery. Among these are messenger RNAs (mRNA), successfully deployed in some prophylactic SARS-CoV2 vaccines. To enhance the immunogenicity of mRNA-deliver...

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Detalles Bibliográficos
Autores principales: Morse, Michael A., Crosby, Erika J., Force, Jeremy, Osada, Takuya, Hobeika, Amy C., Hartman, Zachary C., Berglund, Peter, Smith, Jonathan, Lyerly, H. Kim
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group US 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9911953/
https://www.ncbi.nlm.nih.gov/pubmed/36765179
http://dx.doi.org/10.1038/s41417-023-00587-1