Cargando…
Clinical trials of self-replicating RNA-based cancer vaccines
Therapeutic cancer vaccines, designed to activate immune effectors against tumor antigens, utilize a number of different platforms for antigen delivery. Among these are messenger RNAs (mRNA), successfully deployed in some prophylactic SARS-CoV2 vaccines. To enhance the immunogenicity of mRNA-deliver...
Autores principales: | Morse, Michael A., Crosby, Erika J., Force, Jeremy, Osada, Takuya, Hobeika, Amy C., Hartman, Zachary C., Berglund, Peter, Smith, Jonathan, Lyerly, H. Kim |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group US
2023
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9911953/ https://www.ncbi.nlm.nih.gov/pubmed/36765179 http://dx.doi.org/10.1038/s41417-023-00587-1 |
Ejemplares similares
-
Long-term survival of patients with stage III colon cancer treated with VRP-CEA(6D), an alphavirus vector that increases the CD8+ effector memory T cell to Treg ratio
por: Crosby, Erika J, et al.
Publicado: (2020) -
Cancer vaccine strategies using self-replicating RNA viral platforms
por: Dailey, Gabrielle P., et al.
Publicado: (2022) -
Beyond Neoantigens: Antigens Derived from Tumor Drivers as Cancer Vaccine Targets
por: Crosby, Erika J., et al.
Publicado: (2023) -
Cancer vaccines: the importance of targeting oncogenic drivers and the utility of combinations with immune checkpoint inhibitors
por: Crosby, Erika J., et al.
Publicado: (2021) -
Polyfunctional anti-human epidermal growth factor receptor 3 (anti-HER3) antibodies induced by HER3 vaccines have multiple mechanisms of antitumor activity against therapy resistant and triple negative breast cancers
por: Osada, Takuya, et al.
Publicado: (2018)