The actin bundling activity of ITPKA mainly accounts for its migration-promoting effect in lung cancer cells

Expression of Ins(1,4,5)P(3)-kinase-A (ITPKA), the neuronal isoform of Ins(1,4,5)P(3)-kinases, is up-regulated in many tumor types. In particular, in lung cancer cells this up-regulation is associated with bad prognosis and it has been shown that a high level of ITPKA increases migration and invasio...

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Detalles Bibliográficos
Autores principales: Küster, Lukas, Paraschiakos, Themistoklis, Karakurt, Kader Ebru, Schumacher, Udo, Diercks, Björn-Philipp, Windhorst, Sabine
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Portland Press Ltd. 2023
Materias:
Cancer
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9912108/
https://www.ncbi.nlm.nih.gov/pubmed/36688944
http://dx.doi.org/10.1042/BSR20222150

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9912108/
https://www.ncbi.nlm.nih.gov/pubmed/36688944
http://dx.doi.org/10.1042/BSR20222150

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