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The actin bundling activity of ITPKA mainly accounts for its migration-promoting effect in lung cancer cells
Expression of Ins(1,4,5)P(3)-kinase-A (ITPKA), the neuronal isoform of Ins(1,4,5)P(3)-kinases, is up-regulated in many tumor types. In particular, in lung cancer cells this up-regulation is associated with bad prognosis and it has been shown that a high level of ITPKA increases migration and invasio...
| Autores principales: | , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Portland Press Ltd.
2023
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9912108/ https://www.ncbi.nlm.nih.gov/pubmed/36688944 http://dx.doi.org/10.1042/BSR20222150 |