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Evaluation of a Combined MHE-NMPC Approach to Handle Plant-Model Mismatch in a Rotary Tablet Press

The transition from batch to continuous processes in the pharmaceutical industry has been driven by the potential improvement in process controllability, product quality homogeneity, and reduction of material inventory. A quality-by-control (QbC) approach has been implemented in a variety of pharmac...

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Detalles Bibliográficos
Autores principales: Huang, Yan-Shu, Sheriff, M. Ziyan, Bachawala, Sunidhi, Gonzalez, Marcial, Nagy, Zoltan K., Reklaitis, Gintaras V.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9912115/
https://www.ncbi.nlm.nih.gov/pubmed/36776491
http://dx.doi.org/10.3390/pr9091612