Cargando…

Osthole Antagonizes Microglial Activation in an NRF2-Dependent Manner

Microglia are neuroglia in the brain with an innate immune function and participate in the progress of neurodegenerative diseases. Osthole (OST) is a coumarin derivative extracted from Cnidium monnieri and bears a microglia-antagonizing ability. However, the underlying mechanism of the antagonism is...

Descripción completa

Detalles Bibliográficos
Autores principales: Liu, Chuan-Hsiu, Chen, Mei-Ying, Kuo, Yueh-Hsiung, Cheng, Jack, Chang, Li-Zhong, Chang, Meng-Shiun, Chuang, Tsai-Ni, Hsieh, Wen-Tsong, Xiao, Yan-Ru, Wu, Bor-Tsang, Lin, Wei-Yong, Liu, Hsin-Ping
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9912252/
https://www.ncbi.nlm.nih.gov/pubmed/36677566
http://dx.doi.org/10.3390/molecules28020507