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Selective Synthesis of Lysine Peptides and the Prebiotically Plausible Synthesis of Catalytically Active Diaminopropionic Acid Peptide Nitriles in Water

[Image: see text] Why life encodes specific proteinogenic amino acids remains an unsolved problem, but a non-enzymatic synthesis that recapitulates biology’s universal strategy of stepwise N-to-C terminal peptide growth may hold the key to this selection. Lysine is an important proteinogenic amino a...

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Detalles Bibliográficos
Autores principales: Thoma, Benjamin, Powner, Matthew W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2023
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9912261/
https://www.ncbi.nlm.nih.gov/pubmed/36700882
http://dx.doi.org/10.1021/jacs.2c12497