Integrative Ligand-Based Pharmacophore Modeling, Virtual Screening, and Molecular Docking Simulation Approaches Identified Potential Lead Compounds against Pancreatic Cancer by Targeting FAK1

Pancreatic cancer is a very deadly disease with a 5-year survival rate, making it one of the leading causes of cancer-related deaths globally. Focal adhesion kinase 1 (FAK1) is a ubiquitously expressed protein in pancreatic cancer. FAK, a tyrosine kinase that is overexpressed in cancer cells, is cru...

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Detalles Bibliográficos
Autores principales: Molla, Mohammad Habibur Rahman, Aljahdali, Mohammed Othman, Sumon, Md Afsar Ahmed, Asseri, Amer H., Altayb, Hisham N., Islam, Md. Shafiqul, Alsaiari, Ahad Amer, Opo, F. A. Dain Md, Jahan, Nushrat, Ahammad, Foysal, Mohammad, Farhan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9912262/
https://www.ncbi.nlm.nih.gov/pubmed/36678617
http://dx.doi.org/10.3390/ph16010120

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9912262/
https://www.ncbi.nlm.nih.gov/pubmed/36678617
http://dx.doi.org/10.3390/ph16010120

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