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Integrative Ligand-Based Pharmacophore Modeling, Virtual Screening, and Molecular Docking Simulation Approaches Identified Potential Lead Compounds against Pancreatic Cancer by Targeting FAK1
Pancreatic cancer is a very deadly disease with a 5-year survival rate, making it one of the leading causes of cancer-related deaths globally. Focal adhesion kinase 1 (FAK1) is a ubiquitously expressed protein in pancreatic cancer. FAK, a tyrosine kinase that is overexpressed in cancer cells, is cru...
Autores principales: | Molla, Mohammad Habibur Rahman, Aljahdali, Mohammed Othman, Sumon, Md Afsar Ahmed, Asseri, Amer H., Altayb, Hisham N., Islam, Md. Shafiqul, Alsaiari, Ahad Amer, Opo, F. A. Dain Md, Jahan, Nushrat, Ahammad, Foysal, Mohammad, Farhan |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9912262/ https://www.ncbi.nlm.nih.gov/pubmed/36678617 http://dx.doi.org/10.3390/ph16010120 |
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