Genetic Perturbation Alters Functional Substates in Alkaline Phosphatase

[Image: see text] Enzymes inherently exhibit molecule-to-molecule heterogeneity in their conformational and functional states, which is considered to be a key to the evolution of new functions. Single-molecule enzyme assays enable us to directly observe such multiple functional states or functional...

Descripción completa

Detalles Bibliográficos
Autores principales: Sakuma, Morito, Honda, Shingo, Ueno, Hiroshi, Tabata, Kazuhito V., Miyazaki, Kentaro, Tokuriki, Nobuhiko, Noji, Hiroyuki
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2023
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9912328/
https://www.ncbi.nlm.nih.gov/pubmed/36706363
http://dx.doi.org/10.1021/jacs.2c06693

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9912328/
https://www.ncbi.nlm.nih.gov/pubmed/36706363
http://dx.doi.org/10.1021/jacs.2c06693

Ejemplares similares