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Genetic Perturbation Alters Functional Substates in Alkaline Phosphatase
[Image: see text] Enzymes inherently exhibit molecule-to-molecule heterogeneity in their conformational and functional states, which is considered to be a key to the evolution of new functions. Single-molecule enzyme assays enable us to directly observe such multiple functional states or functional...
| Autores principales: | , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
American Chemical Society
2023
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9912328/ https://www.ncbi.nlm.nih.gov/pubmed/36706363 http://dx.doi.org/10.1021/jacs.2c06693 |