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Fully Automated Characterization of Protein–Peptide Binding by Microfluidic 2D NMR
[Image: see text] We demonstrate an automated microfluidic nuclear magnetic resonance (NMR) system that quantitatively characterizes protein–ligand interactions without user intervention and with minimal sample needs through protein-detected heteronuclear 2D NMR spectroscopy. Quantitation of protein...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
American Chemical Society
2023
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9912330/ https://www.ncbi.nlm.nih.gov/pubmed/36716203 http://dx.doi.org/10.1021/jacs.2c13052 |