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Orientation-Locked DNA Origami for Stable Trapping of Small Proteins in the Nanopore Electro-Osmotic Trap

[Image: see text] Nanopores are versatile single-molecule sensors offering a simple label-free readout with great sensitivity. We recently introduced the nanopore electro-osmotic trap (NEOtrap) which can trap and sense single unmodified proteins for long times. The trapping is achieved by the electr...

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Detalles Bibliográficos
Autores principales: Wen, Chenyu, Bertosin, Eva, Shi, Xin, Dekker, Cees, Schmid, Sonja
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2022
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9912335/
https://www.ncbi.nlm.nih.gov/pubmed/36507712
http://dx.doi.org/10.1021/acs.nanolett.2c03569