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SampleQC: robust multivariate, multi-cell type, multi-sample quality control for single-cell data
Quality control (QC) is a critical component of single-cell RNA-seq (scRNA-seq) processing pipelines. Current approaches to QC implicitly assume that datasets are comprised of one cell type, potentially resulting in biased exclusion of rare cell types. We introduce SampleQC, which robustly fits a Ga...
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9912498/ https://www.ncbi.nlm.nih.gov/pubmed/36765378 http://dx.doi.org/10.1186/s13059-023-02859-3 |