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SampleQC: robust multivariate, multi-cell type, multi-sample quality control for single-cell data

Quality control (QC) is a critical component of single-cell RNA-seq (scRNA-seq) processing pipelines. Current approaches to QC implicitly assume that datasets are comprised of one cell type, potentially resulting in biased exclusion of rare cell types. We introduce SampleQC, which robustly fits a Ga...

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Detalles Bibliográficos
Autores principales: Macnair, Will, Robinson, Mark
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9912498/
https://www.ncbi.nlm.nih.gov/pubmed/36765378
http://dx.doi.org/10.1186/s13059-023-02859-3