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ABCB5(+) mesenchymal stromal cells therapy protects from hypoxia by restoring Ca(2+) homeostasis in vitro and in vivo

BACKGROUND: Hypoxia in ischemic disease impairs Ca(2+) homeostasis and may promote angiogenesis. The therapeutic efficacy of mesenchymal stromal cells (MSCs) in peripheral arterial occlusive disease is well established, yet its influence on cellular Ca(2+) homeostasis remains to be elucidated. We ad...

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Detalles Bibliográficos
Autores principales: Yan, Kaixuan, Zheng, Jiaxing, Kluth, Mark Andreas, Li, Lin, Ganss, Christoph, Yard, Benito, Magdeburg, Richard, Frank, Markus H., Pallavi, Prama, Keese, Michael
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9912525/
https://www.ncbi.nlm.nih.gov/pubmed/36759868
http://dx.doi.org/10.1186/s13287-022-03228-w