Inhibition of MMPs supports amoeboid angiogenesis hampering VEGF-targeted therapies via MLC and ERK 1/2 signaling

BACKGROUND: In the past decades studies on anti-tumoral drugs inhibiting matrix metalloproteinase (MMPs) were disappointing. Recently, we demonstrated that mature endothelial cells (ECs) and endothelial colony forming cells (ECFCs) can switch between invasion modes to cope with challenging environme...

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Detalles Bibliográficos
Autores principales: Chillà, Anastasia, Anceschi, Cecilia, Frediani, Elena, Scavone, Francesca, Del Rosso, Tommaso, Pelagio, Giuseppe, Tufaro, Antonio, De Palma, Giuseppe, Del Rosso, Mario, Fibbi, Gabriella, Chiarugi, Paola, Laurenzana, Anna, Margheri, Francesca
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9912547/
https://www.ncbi.nlm.nih.gov/pubmed/36759828
http://dx.doi.org/10.1186/s12967-023-03954-6

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9912547/
https://www.ncbi.nlm.nih.gov/pubmed/36759828
http://dx.doi.org/10.1186/s12967-023-03954-6

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