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When a joint model should be preferred over a linear mixed model for analysis of longitudinal health-related quality of life data in cancer clinical trials

BACKGROUND: Patient-reported outcomes such as health-related quality of life (HRQoL) are increasingly used as endpoints in randomized cancer clinical trials. However, the patients often drop out so that observation of the HRQoL longitudinal outcome ends prematurely, leading to monotone missing data....

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Detalles Bibliográficos
Autores principales: Touraine, Célia, Cuer, Benjamin, Conroy, Thierry, Juzyna, Beata, Gourgou, Sophie, Mollevi, Caroline
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9912607/
https://www.ncbi.nlm.nih.gov/pubmed/36765307
http://dx.doi.org/10.1186/s12874-023-01846-3