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GDNF-RET signaling and EGR1 form a positive feedback loop that promotes tamoxifen resistance via cyclin D1

BACKGROUND: Rearranged during transfection (RET) tyrosine kinase signaling has been previously implicated in endocrine resistant breast cancer, however the mechanism by which this signaling cascade promotes resistance is currently not well described. We recently reported that glial cell-derived neur...

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Detalles Bibliográficos
Autores principales: Marks, Brooke A., Pipia, Ilissa M., Mukai, Chinatsu, Horibata, Sachi, Rice, Edward J., Danko, Charles G., Coonrod, Scott A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9912664/
https://www.ncbi.nlm.nih.gov/pubmed/36765275
http://dx.doi.org/10.1186/s12885-023-10559-1