Cargando…
GDNF-RET signaling and EGR1 form a positive feedback loop that promotes tamoxifen resistance via cyclin D1
BACKGROUND: Rearranged during transfection (RET) tyrosine kinase signaling has been previously implicated in endocrine resistant breast cancer, however the mechanism by which this signaling cascade promotes resistance is currently not well described. We recently reported that glial cell-derived neur...
Autores principales: | Marks, Brooke A., Pipia, Ilissa M., Mukai, Chinatsu, Horibata, Sachi, Rice, Edward J., Danko, Charles G., Coonrod, Scott A. |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2023
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9912664/ https://www.ncbi.nlm.nih.gov/pubmed/36765275 http://dx.doi.org/10.1186/s12885-023-10559-1 |
Ejemplares similares
-
A bi-stable feedback loop between GDNF, EGR1, and ERα contribute to endocrine resistant breast cancer
por: Horibata, Sachi, et al.
Publicado: (2018) -
ER-positive breast cancer cells are poised for RET-mediated endocrine resistance
por: Horibata, Sachi, et al.
Publicado: (2018) -
GDNF and the RET Receptor in Cancer: New Insights and Therapeutic Potential
por: Mulligan, Lois M.
Publicado: (2019) -
Acute stress disrupts intestinal homeostasis via GDNF‐RET
por: Lin, Lin, et al.
Publicado: (2020) -
RET-independent signaling by GDNF ligands and GFRα receptors
por: Ibáñez, Carlos F., et al.
Publicado: (2020)