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Right-handed Z-DNA at ultrahigh resolution: a tale of two hands and the power of the crystallographic method
The self-complementary l-d(CGCGCG)(2) purine/pyrimidine hexanucleotide was crystallized in complex with the polyamine cadaverine and potassium cations. Since the oligonucleotide contained the enantiomeric 2′-deoxy-l-ribose, the Z-DNA duplex is right-handed, as confirmed by the ultrahigh-resolution c...
| Autores principales: | , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
International Union of Crystallography
2023
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9912920/ https://www.ncbi.nlm.nih.gov/pubmed/36762859 http://dx.doi.org/10.1107/S2059798322011937 |